The automated thermal cycler Biometra TRobot II allows a high-throughput PCR workflow with 24/7 reliable, unattended operation with highest quality of results for routine PCR or incubation applications. It is ideal for molecular biology labs that face a large number of samples every day and need to rely on the analysis results of their valuable samples.
High Degree of Automation for More Efficiency
- Space-saving modular concept
- Direct access to the sample block from three sides
- Trouble-free removal of plates thanks patent-pending plate lifting system
- Gradient function for optimization of new protocols
- Touch-sensitive safety frame at the lid for maximum user-safety
- Robust design for 24/7 use in automated systems
- Patent-pending automated Smart Tune Lid ensures uniform conditions in all sample positions
Product Highlights in Detail
Always best results
In addition to the typical main application, the polymerase chain reaction (PCR), the Biometra TRobot II is also suitable for all other molecular biological or chemical incubations in PCR plates. For example, the generation of libraries for Next Generation Sequencing (NGS) is an important step in a larger workflow where the automated thermal cycler can be used. This reduces the manual effort and the possibility of errors. The PCR cycler has outstanding heating and cooling rates and excellent temperature homogeneity across the sample block for highly reproducible PCR results. For the setup of new protocols or for the transfer of existing protocols from other thermal cyclers it is sometimes necessary to make slight optimizations to the protocols. For this purpose the Biometra TRobot II includes a gradient function. With this function it is possible, to test different temperatures in the critical annealing step of the PCR in one run.
Fit for integration
In automated systems, compact components with the smallest possible footprint are particularly important. The Biometra TRobot II meets this requirement through its modular design with a compact PCR module that is placed directly on the automation deck, while the controller can be stored underneath the platform. Another important point in automation is that all components should be very robust and reliable. If one component fails, the entire workflow comes to a halt. With this background, we have developed a special, patent-pending mechanism for opening and closing the lid of the Biometra TRobot II, which is intended for permanent use. At the same time, the block design was designed to enable the gripper to access the sample block from three sides. This opens up many possibilities for positioning the thermal cycler on the deck.
Ease of work
A conveniently prepared library allows a fast integration into automation systems. In addition, powerful computer software, the Biometra TSuite, is available for direct control of the automated thermal cycler, which is helpful for first PCR runs in preparation for the actual application. Maximum user safety is ensured with a unique, touch-sensitive safety frame which immediately stops the lid closing in case of contact with a resistance. The smooth block surface without gaps is essential for easy and effective cleaning and decontamination. For stress-free work it is also important to keep the noise level low. The ventilation system has been designed to remain very quiet, even at high performance levels. This allows you to work next to Biometra TRobot II concentrated!
Technology Highlights
Smart Tune Lid concept
The unique arc-shaped opening movement has many advantages: In addition to a low instrument height, the sample block is completely accessible for the gripper from three sides. The vertical closing of the lid with software adjustable pressure on the sample plate ensures completely uniform conditions in all sample positions regardless of the height of the plate and sealing material. This feature ensures best reproducibility of results. The particularly robust and patent-pending single-motor mechanism is ideally designed for 24/7 use.
Smart release of plates
For a workflow without interruptions it is very important that the sample plate can be removed smoothly from the block. Since plates can get stuck on the block after long incubation at different temperatures, the Biometra TRobot II contains a patent-pending system with four small motor-driven plate lifters. When the lid is opened, they gently lift the plate out of the block and are then immediately recessed. This unique system is compatible with all full-skirted plates. A simple adapter frame is available for half-skirted plates.
